AstraZeneca, the world's biggest drugmaker, has announced the discontinuation of its antidepressant Seroquel (quetiapine fumarate) from its schizophrenia treatment, Seroquel XR.
The company's withdrawal from Seroquel from the market comes at a time when AstraZeneca is looking to expand its lead by up to a year.
In April, AstraZeneca announced the discontinuation of Seroquel XR due to a report that showed Seroquel XR had a risk of increasing suicidal thinking and behavior. The safety data came from the study, which showed that patients receiving Seroquel XR had a greater risk of developing suicide attempts compared to those receiving placebo.
The withdrawal was made in part by the announcement of an AstraZeneca settlement, which will cover about $2.5 billion of the transaction. This includes $1.3 billion in upfront and $2.5 billion in cash, plus a total of $2.5 billion in shares of the company.
AstraZeneca will continue to pay the affected shareholders and other affected parties, including shareholders of the company's stock, or in some cases, its shareholders and other affected shareholders, and it will pay the affected shareholders an additional $300 million in compensation.
Seroquel XR, or quetiapine fumarate, is a branded treatment used to treat schizophrenia in adults and children ages 12 and older, among others. AstraZeneca has since withdrawn its Seroquel XR from the market and the company is seeking to sell its Seroquel XR in the US.
Source-Medindia
Medindia is a direct-to-consumer newspaper owned by AstraZeneca. Medindia is a subsidiary of the company that serves as a distributor to the major online pharmacies. The Company is a member of the New York Stock Exchange.Medindia.com.com is a direct-to-consumer online pharmacy owned by AstraZeneca.SOURCE Medindia
AstraZenecahttps://medindia.Atypical antipsychotics can cause a number of side effects. Common ones include nausea, vomiting, constipation, dry mouth, dizziness, constipation, insomnia, decreased appetite, decreased sexual ability, and increased risk for suicide.
Atypical antipsychotics, such as quetiapine (Seroquel), quetiapine (Seroquel XR), risperidone (Risperdal), and ziprasidone (Geodon), can cause a number of side effects. These side effects usually go away on their own within weeks. However, some of these side effects may get worse over time. For example, if you begin to experience dry mouth, dizziness, decreased energy, or sleepiness, you may experience insomnia, constipation, increased appetite, weight gain, increased blood sugar levels, and an increased risk for suicide.
It’s important to note that these side effects are not a new problem. More research is needed to fully understand what the effects of these medications are and how they can be avoided.
Atypical antipsychotics typically begin to work within a few weeks of starting medication. They can take about an hour to start working, and they can last for up to several weeks, which is a big difference. Atypical antipsychotics work by reducing the amount of dopamine in the brain, which is the key neurotransmitter that influences mood.
The antipsychotics that work best for you can be divided into two main categories: (1) stimulants (such as clozapine), and (2) mood stabilizers (such as selegiline). Stimulant drugs work by changing the amount of neurotransmitters in the brain. This means that a certain amount of serotonin and dopamine (the two main types of serotonin) can be reabsorbed back into nerve cells, which then lead to a more intense effect.
If your antipsychotic medication doesn’t seem to be working right for you, talk to your doctor. They may be able to suggest an alternative or additional treatment option. They can also help you feel more relaxed and more confident about your mental health. Your doctor will want to see if you are still having any side effects from the medication, so they can help you manage them more effectively.
There are several different antipsychotic medications that can take a long time to work. Atypical antipsychotics typically take about an hour to start working. Atypical antipsychotics are not addictive. They have a low potential for abuse and addiction, and they tend to be less likely to cause problems with suicide.
Atypical antipsychotics do not cause withdrawal symptoms in the short term. They can make your body feel sleepy, tired, and less alert, which can be a major problem with long-term antipsychotic use. This is because antipsychotics work by balancing the amount of dopamine and serotonin in the brain.
You may still experience some short term side effects, such as changes in mood, anxiety, or depression. These changes can last for a few weeks or months, and you may experience more serious side effects if you continue to use them. If you continue to have these side effects, talk to your doctor.
If you have questions about the side effects of atypical antipsychotics, talk with your doctor. They can help you understand how these side effects can be managed or may recommend an alternative treatment option.
If you have questions about the potential risk of a dangerous event in your personal or professional life, there is no reason to panic. If you have concerns about your mental health, or have a history of suicidal thoughts or actions, call your doctor right away. You may be able to get help right away if you are diagnosed with bipolar disorder or depression.
The most common side effects of antipsychotic medications include drowsiness, dry mouth, increased appetite, insomnia, increased heart rate, and increased body temperature. These side effects are typically mild and temporary.
It’s important to note that antipsychotic medications can also have long-term effects, and they can affect a person’s ability to carry out their mental health, especially if you are over the age of 60. This is especially true for people with a history of substance abuse or bipolar disorder.
Atypical antipsychotics are typically prescribed in combination with other medications and treatment, and they may be prescribed for a limited number of days.
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SEROQUEL Quetiapine (300mg) 60 Extended Release TabletsQuetiapine is the branded version of the generic medication known as Seroquel. It is taken orally or by tablet and is not regulated as any Meds Healthylife product (i.e. Seroquel XR) is supplied by Healthylife.
Quetiapine is a member of the antipsychotic drugs class and is used to treat:
Quetiapine is usually taken twice daily, preferably at the same time of day, with or without food. The duration of treatment can be up to three weeks. Quetiapine may be taken with or without food. Quetiapine is not recommended for use in patients who have had a major depressive episode.
Quetiapine may interact with other medications, thereby it is important to inform your doctor of any other medications you are taking prior to beginning a potentially dangerous medication interactions.
Quetiapine may also interact with other drugs including blood thinners such as warfarin and phenytoin. If you have been advised to stop taking quetiapine before the first day of your planned activity, does your doctor monitor your blood pressure while you are taking this medication?
Quetiapine contains the active ingredient quetiapine fumarate, which is a mixture of two salts: quetiapine and sodium quetiapine. The two salts are identical in strength and do not contain the same active ingredient. The main active ingredient of quetiapine is quetiapine, which is a brand name for the medication.
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Healthylife is a generic medication in a class of drugs known as lipase inhibitors. It works by stopping the body from making more of the hormones that are normally produced by the body. When Seroquel XR is taken orally, the tablets are absorbed by the body into the stomach and cause a release of serotonin and dopamine from the brain, resulting in a feeling of excitement and a decrease in negative symptoms.